October 31st, 2012
- Biophysics, molecular biology, nanotechnology
- Atomic force microscopy for imaging and manipulating molecules, nanoscopic fibers and cells
- Laser scanning confocal fluorescence microscopy and regular fluorescence microscopy (combined with the atomic-force microscope)
- Next-generation genetic sequencing using the Ion Torrent Personal Genome Machine by Life Technologies
- Using nanotechnology and next-generation genetic sequencing for drug discovery.
- Studying fibrin fibers in blood clots to find new treatments for heart attacks and strokes.
- Investigating how normal cells and cancerous cells differ, focusing on breast cancer cells.
- Studying electrospun fibrin, collagen and synthetic polymer nanofibers to use as scaffolds in repairing or rebuilding tissue.
- Introductory Physics
- Quantum Physics
- Calculus-based, General Physics
- Biophysics Methods Lab
- Physics Research
- Ph.D., M.A., University of Oregon
- Vordiplom (B.S.), Universität Ulm, Germany
- “α−α Crosslinks Increase Fibrin Fiber Elasticity and Stiffness,” Biophysical Journal, 2012
- “The Mechanical Properties of Dry, Electrospun Fibrinogen Fibers,” Materials Science and Engineering, 2012
- “Fibrinogen Unfolding Mechanisms Are Not Too Much of a Stretch,” Structure, 2011
- “Selection of Bead-Displayed, PNA-encoded Chemicals,” Journal of Molecular Recognition, 2010
Using beads so tiny that 1,000 of them would fit across a strand of human hair, Martin Guthold hopes to find the next treatment for cancer – or any other disease, for that matter. His discoveries come in such small packages via a tool he and his partners invented. It’s called Next-Gen Lab-on-Bead. Continue reading »
October 1st, 2012
- Medicinal chemistry
- Platinum- and gold-based drugs
- Cancer biology and treatments
- Drug discovery and testing
- Bioinorganic chemistry
- Combinatorial chemistry
- Manipulating nucleic acid structures
- DNA-targeted platinum–acridine anticancer agents
- Targeting and probing unusual disease-related nucleic acid structures
- Therapies that disrupt aberrant growth signals in cancer cells
- Inorganic Chemistry
- Bioinorganic Chemistry
- General Chemistry
- Molecules to Medicines
- B.S. and Ph.D., University of Oldenburg, Germany
- L. A. Graham, J. Suryadi, T. K. West, G. L. Kucera, U. Bierbach: Synthesis, Aqueous Reactivity, and Biological Evaluation of Carboxylic Acid Ester-Functionalized Platinum–Acridine Hybrid Anticancer Agents. Journal of Medicinal Chemistry, 55, 7817–7827 (2012).
- X. Qiao, A. E. Zeitany, M. W. Wright, A. S. Essader, K. E. Levine, U. Bierbach: Analysis of the DNA damage produced by a platinum–acridine antitumor agent and its effects in NCI-H460 lung cancer cells. Metallomics, 4, 645-652 (2012).
- C. L. Smyre, G. Saluta, T. E. Kute, G. L. Kucera, U. Bierbach: Inhibition of DNA Synthesis by a Platinum–Acridine Hybrid Agent Leads to Potent Cell Kill in Non-Small Cell Lung Cancer. ACS Medicinal Chemistry Letters, 2, 870-874 (2011).
- H. Kostrhunova, J. Malina, A. J. Pickard, J. Stepankova, M. Vojtiskova, J. Kasparkova, T. Muchova, M. L. Rohlfing, U. Bierbach, V. Brabec: Replacement of a Thiourea with an Amidine Group in a Monofunctional Platinum–Acridine Antitumor Agent. Effect on DNA Interactions, DNA Adduct Recognition and Repair. Mol. Pharmaceutics, 8, 1941-1954 (2011).
- L. A. Graham, G. M. Wilson, T. K. West, C. S. Day, G. L. Kucera, U. Bierbach: Unusual Reactivity of a Potent Platinum-Acridine Hybrid Antitumor Agent. ACS Medicinal Chemistry Letters, 2, 687-691 (2011).
- J. R. Choudhury, L. Rao, U. Bierbach: Rates of intercalator-driven platination of DNA determined by restriction enzyme cleavage inhibition assay. Journal of Biological Inorganic Chemistry, 16, 373-380 (2011).
Uli Bierbach’s interdisciplinary drug discovery research spans the fields of organic and inorganic synthesis, medicinal chemistry, biophysical chemistry, and molecular and cellular biology. His professional expertise in the sciences and personal passion for improving cancer survival rates have resulted in platinum-based treatments that kill non-small cell lung cancer cells at 500 times the rate of most available treatments. Continue reading »
September 27th, 2012
- Theoretical and computational research in condensed matter physics to better understand the behavior and characteristics of materials. This research supports the design of new, improved and advanced materials for use in all types of technology.
- Testing hydrogen-storage options to facilitate the use of hydrogen to power vehicles.
- Investigating metal organic framework materials for gas sequestration and carbon capture, to control the release of greenhouse gasses.
- Calculating nuclear magnetic resonance chemical shifts to better understand the structure of materials ranging from water to human DNA.
- General physics
- Condensed matter physics
- Quantum physics
- Ph.D., M.S., B.S., Karl-Franzens-Universität, Austria
- “Tuning the gate opening pressure of metal organic frameworks (MOFs) for the selective separation of hydrocarbons,” Journal of the American Chemical Society, 2012
- “Molecular biology at the quantum level: Can modern density functional theory forge the path?” Nano LIFE, 2012
- “van der Waals density functional study of energetic, structural, and vibrational properties of small water clusters and ice,” Physical Review, 2011
Timo Thonhauser sees much potential for using hydrogen to power vehicles. Hydrogen is plentiful and every nation has access to it. It burns clean, so the only byproduct is water. And the world’s fossil fuels are running out – so we need another option. Continue reading »
July 18th, 2012
- Neural control of physiology and behavior
- Molecular biology
- Biological oscillators
- Neural circuits and fruit flies
- Role of AMP-activated kinase in signaling hormones to release energy stores under starvation conditions
- Neuronal cell signaling
- Neurotransmitters and their receptors
- Neural circuits
- B.A. and Ph.D., University of Maine
- “Altered metabolism and persistent starvation phenotypes caused by reduced AMP-activated kinase function in Drosophila,” PLoS ONE, 2010
- “Corazonin neurons participate in sexually dimorphic circuitry that shape behavioral responses to stress in Drosophila,” PLoS ONE, 2010
- “Functional differences between two CRF-Related Diuretic Hormone Receptors in Drosophila,” Journal of Experimental Biology, 2009
Erik Johnson is one of the country’s leading researchers of neural systems in the fruit fly Drosophila, using his findings as a model for neurobiological systems in humans. In 2005, his research team discovered that, since fruit fly and human brains are wired the same way, one group of cells is responsible for a specific hormone release. That finding has informed his current research on how fruit flies respond to stress and the manipulation of the release of energy stores in the cells. Continue reading »
July 17th, 2012
- Artificial Intelligence
- Computer Security
- Probabilistic Reasoning
- Multiagent Systems
Ongoing Collaborative Research
- Modeling biological networks and sequence motifs employed in hormonal control of phenylpropanoid synthesis
- Development of computational algebra and Bayesian tools for biological modeling
- Modeling signaling networks and transcriptional regulatory networks in osteoarthritis
- Discovering host intent through network motif analysis
- Advanced Android Programming
- Computational Systems Biology
- Programming Languages
- B.S., College of Charleston
- Ph.D., University of South Carolina
- “Engaging the community with mobile app projects.” William H. Turkett, Jr., V. Paúl Pauca, Joel Hollingsworth. In Proceedings of the 43rd ACM Technical Symposium on Computer Science Education, 2012.
- “Graph mining of motif profiles for computer network activity inference.” William H. Turkett Jr., Errin W. Fulp, Charles Lever, and Eddie Allan. In Proceedings of the Ninth Workshop on Mining and Learning with Graphs (MLG 2011), 2011. PDF available here
- “Comparison of co-temporal modeling algorithms on sparse experimental time series data sets.” Edward E. Allen, James L. Norris, David J. John, Stan J. Thomas, William H. Turkett Jr., Jacquelyn S. Fetrow. In Proceedings of the 2010 IEEE International Conference on Bioinformatics and Bioengineering, 2010. Online article here
- “Using network motifs to identify application protocols.” Eddie G. Allan, William H. Turkett, and Errin W. Fulp. In Proceedings of the IEEE Global Communications Conference, 2009. PDF available here
The world around us is filled with patterns. Over time, the inputs and outputs of a system reveal their data patterns to the trained eye. William Turkett is one of those trained eyes. His current work applies the analysis techniques of computational biology to the urgent problems of computer security in an effort to discover groups of malevolent agents from the communication trails they leave behind. Continue reading »
June 7th, 2012
- Environmental issues
- Climate change
- Tropical Conservation
- Cloud Forests
- Large-scale species distribution in the western Andes and Amazon
- Paleoecology and response to climate change of Andean and Amazonian forest trees
- Plant-animal interactions and community structure and diversity
- The effects of humans on Amazonian and Andean ecosystems
- The exploration of little-known ecosystems in South America, particularly the bamboo forest and Andean forest
- The use of remote sensing to determine carbon content and deforestation rates
- Conservation of the last wild places in the Amazon and Andes
- The role of animals in tropical forests
- The distribution of tropical species and their responses to climate change
- Estimating extinction rates in high-biodiversity areas
- Tropical Ecology
- Tropical Biodiversity
- Community Ecology
- Plant Evolution
- Plant Ecology
- Techniques in Mathematical Biology
- Advanced Ecology
- B.S., University of Missouri
- Ph.D., Duke University
- “Sparse Pre-Columbian Human Habitation in Western Amazonia,” Science, June 2012
- “The upward migration of Andean trees in response to increasing temperatures,” Journal of Biogeography, April 2011
- “Extinction rates of Amazonian plant species,” Proceedings of the National Academy of Sciences, July 2009
- “Land-use and climate change effects on population size and extinction risk of Andean plants,” Global Change Biology, February 2010
- “Ecosystem carbon storage across the grassland-forest transition in the high Andes of Manu National Park, Peru,” Ecosystems, September 2010
As a conservation biologist, Miles Silman has been a leader in the sustainability movement since beginning his doctoral research more than 20 years ago. Silman’s work centers on understanding species distributions, biodiversity, and the response of forest ecosystems to climate and land use changes over time. Continue reading »
June 7th, 2012
- Flexible plastics
- Organic electronics
- Organic semiconductors
- Organic devices
- Physics of organic semiconductor devices
- Organic spintronics
- Functional organic materials
- Structure-property correlations
- General Physics 1 & 2
- BS, MS, University of Timisoara (Romania)
- PhD, University of Groningen (The Netherlands)
- H.-J. Jang, O. A. Kirillov, O. D. Jurchescu, and Curt A. Richter, “Spin transport in memristive devices”, Applied Physics Letters. 100, 043510 (2012)
- K. P. Goetz, Z. Li, J. W. Ward, C. Bougher, J. Rivnay, J. Smith, B. R. Conrad, S. R. Parkin, T. D. Anthopoulos, A. Salleo, J. E. Anthony and O. D. Jurchescu, “Effect of Acene Length on Electronic Properties in 5-, 6-, and 7-Ringed Heteroacenes” Advanced Materials. 23, 3698 (2011).
- M. Coll, K. P. Goetz, B. R. Conrad, C. A. Hacker, D. J. Gundlach, C. A. Richter, and O. D. Jurchescu, “Flip chip lamination to electrically contact organic single crystals on flexible substrates”, Applied Physics Letters. 98, 163302 (2011).
- J. W. Owen, N. A. Azarova, M. A. Loth, M. Paradinas, M. Coll, C. Ocal, J. E. Anthony, and O. D. Jurchescu, “Effect of Processing Parameters on Performance of Spray-Deposited Organic Thin-Film Transistors,” Journal of Nanotechnology. 2011, 914510 (2011).
- N. A. Azarova, J. W. Owen, C. A. McLellan, M. A. Grimminger, E. K. Chapman, J. E. Anthony, and O. D. Jurchescu, “Fabrication of Organic Thin-Film Transistors by Spray-Deposition for Low-Cost, Large-Area Electronics”, Org. Electron. 11, 1960 (2010).
Oana Jurchescu’s expertise is in the structure and electronic properties of organic semiconductors, as well as the fabrication and characterization of devices for nano and macroelectronics. Her current research focuses on organic electronics, a technology which has the potential to address unique applications, such as artificial skin, smart bandages, flexible displays, wearable electronics, and more. Jurchescu focuses on understanding the fundamental properties of these materials, and on integrating them with various technologies addressing large-area electronics. Continue reading »
June 7th, 2012
- Japanese Literature, Film, and Culture
- National identity
- Cultural Narratives
- Postmodern Culture
- Japanese Literature
- Japanese Pop Culture
- Japanese Film
- Contemporary East Asian Film
- East Asian Culture
- Advanced Japanese
- BA, MA, Brigham Young
- PhD, UC Berkeley
Selected Publications (forthcoming)
- “Shimada Masahiko’s ‘Sophisticated Masochism’ and Japanese Postwar Subjectivity”
- “Ninja in the Dragon’s Den: Regional Imaginaries in East Asian Action Cinema”
- “The Database Imagination of Japanese Postmodern Culture” Japanese Studies.
Marc Yamada is an expert in Japanese culture, history, modern literature and film. His work challenges people to develop a broader worldview of Japan, a country they might otherwise ignore or misunderstand. For example, in Yamada’s “Japanese literature and East Asian cultures” course, students examine films and books about Pearl Harbor and World War II. Their studies encourage a deeper understanding of important historical events, their impact on previous generations of Americans and their ramifications for the present. Continue reading »
June 6th, 2012
- Particle Physics
- Particle Astrophysics
- Numerical General Relativity
- Semi-Classical Gravity
- Numerical Patterns
- Quantum Mechanics
- General Physics
- Elementary Modern Physics
- Skepticism, Pseudoscience and the Scientific Method
- Particle Physics
- MA, Ph.D, Harvard University
- BS, Michigan State University
- “Semiclassical gravity in the far field limit of stars, black holes, and wormholes,” E. D. Carlson, P. R. Anderson, A. Fabbri, S. Fagnocchi, W. H. Hirsch, and S. A. Klyap, Physical Review D, 82(124070), 23 (2010).
- “Stress-energy Tensor for Massless Spin-1/2 in Static Black Hole Spacetimes,” Eric D. Carlson, William H. Hirsch, Benedikt Obermayer, Paul R. Anderson, and Peter B. Groves, Phys. Rev. Lett. 91, 051301 (2003).
- “Method to compute the stress-energy tensor for the massless spin 1/2 field in a general static spherically symmetric spacetime,” Peter B. Groves, Paul R. Anderson, and Eric D. Carlson, Phys. Rev. D66, 124017 (2002).
- “Black Hole Evolution by Spectral Methods,” Eric D. Carlson, Lawrence E. Kidder, Mark A. Scheel, Saul A. Teukolsky, and Gregory B. Cook, Phys. Rev. D62, 084032 (2000).
- “Pseudoscalar Conversion and X-rays from the Sun,” Eric D. Carlson, Physics Letters B 369, 193 (1996).
- “Photon to Pseudoscalar Conversion in the Interstellar Medium,” Eric D. Carlson and W.D. Garretson, Phys. Lett. B336, 431 (1994).
Having researched particle physics for more than 25 years, Eric Carlson is an expert in understanding how the universe is put together at the most fundamental level.
Though his research on particle astrophysics, numerical general relativity and semi-classical gravity has been published in peer-reviewed scientific journals and gained national recognition, Carlson is also known for his skeptical views on a variety of supernatural and extraordinary claims, including numerology, ghosts, and supposed supernatural powers. Continue reading »
June 5th, 2012
- International Recruiting
- Immersion of International Students into U.S. Colleges
- Tiger Mom Parenting Theories
- College Admissions
- Theology and Biblical Studies
- East Asian Culture
- International Education
- MBA, Wake Forest University
- Ph.D., The Southern Baptist Theological Seminary
- M.Div., The Southern Baptist Theological Seminary
- BA, Meredith College
- McKinnish Bridges, L. (2011). Agrarian Aphorisms in the Gospel of John: An Illustration of John 4:35. Jesus, John, and History: Society of Biblical Literature.
- McKinnish Bridges, L. (2008). 1 & 2 Thessalonians. Macon: Smith & Helwys Publishing.
- McKinnish Bridges, L. (2007). The Fourth Gospel and Celtic Christianity. New York: Edwin Mellen Press.
- McKinnish Bridges, L. (1997). The Church’s Portrait of Jesus. Macon: Smith & Helwys Publishing.
Linda McKinnish Bridges is anything but your typical college recruiter. Her life’s journey has taken her from Baptist ministry in rural North Carolina and Taiwan to building cultural bridges with potential students from Belgium to Beijing. In China, her fluency in Mandarin and understanding of the culture help establish a sense of trust and give Wake Forest a distinct, yet unexpected, advantage in welcoming students to campus. Continue reading »